### Modacare (Modafinil) 200 mg: Overview **Active Ingredient:** Modafinil **Formulation:** Usually available in tablet form, 200 mg dosage. ### Indications Modacare is primarily prescribed for: - **Narcolepsy:** A chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden attacks of sleep. - **Obstructive Sleep Apnea (OSA):** Used as a treatment to improve wakefulness in patients who experience excessive sleepiness despite using continuous positive airway pressure (CPAP). - **Shift Work Sleep Disorder (SWSD):** Helps individuals whose work hours disrupt normal sleep patterns. ### Mechanism of Action Modafinil promotes wakefulness by: - Altering neurotransmitters in the brain, particularly increasing levels of dopamine. - Influencing other neurotransmitter systems, which contributes to its wakefulness-promoting effects. ### Dosage and Administration - **Typical Dosage:** The standard dose is 200 mg taken once daily, usually in the morning. - **Shift Work:** May be taken about an hour before the start of the work shift. ### Side Effects Common side effects may include: - Headaches - Nausea - Dizziness - Insomnia - Anxiety - Dry mouth **Serious side effects** (rare) may include: - Skin rashes (possibly serious) - Allergic reactions - Heart problems (e.g., increased heart rate) - Mood changes (e.g., aggression, depression) ### Contraindications Modacare should not be used in individuals with: - History of hypersensitivity to modafinil or armodafinil. - Severe liver disease. ### Drug Interactions Modafinil can interact with various medications, including: - **Anticoagulants:** May affect warfarin levels. - **Hormonal contraceptives:** Can reduce the effectiveness of birth control pills. - **Other stimulants:** May increase the risk of side effects. ### Precautions - **Medical History:** Inform your doctor about any history of heart problems, mental health issues, or liver disease. - **Pregnancy/Breastfeeding:** Consult a healthcare provider if pregnant or breastfeeding. ### Monitoring Regular follow-up with a healthcare provider is recommended to monitor efficacy and side effects, especially during the initial treatment period. ### Conclusion Modacare 200 mg can be effective for promoting wakefulness in specific sleep disorders but should be used under medical supervision to ensure safety and effectiveness. Always consult with a healthcare professional for personalized advice and before starting or stopping any medication.